After 10 years of severe menopause symptoms, hot flashes, night sweats, depression, insomnia and poor skin and nails, I had tried nearly every OTC product out there. Finding Smoky Mountain Natural Estro-life and Progesto-life restored my sanity! To anyone new trying this product, it does take several weeks to work to maximum effect, (at least for me), but my symptoms are now completely non-existent and I feel like a new person. Twice in the months I have been on these creams, I did not refill them before I ran out, (I have to admit I hoped that I was past menopause problems), and all symptoms gradually returned. Now I make sure to always order early! The customer service is always superb too. Could not rate this product any higher.