Tadalista 40 mg is a particular, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Phosphodiesterase type 5 is a protein present mostly in the smooth muscle of the corpus cavernosum that selectively claves and discredits the cyclic guanosine monophosphate (cGMP) to 5’guanosine monophosphate (5’GMP).